Case | Chr | Start | End | Gene | Genetic alteration | |
---|---|---|---|---|---|---|
2 | Chr10 | 89,624,156 | 89,725,266 | PTEN | Del | TC was reported in patients with Cowden syndrome, which is caused by germline PTEN deletion [6]. PTEN mutation is found in glioblastoma, endometrial carcinoma, lymphoma, thyroid, breast, prostate carcinoma, melanoma [12]. |
3 | Chr20 | 39,657,593 | 39,752,015 | TOP1 | Amp | TOP1 amplification was reported in advanced and poor prognostic tumors in melanoma [13]. |