ORR | DCR | R0R1 resection | TTP, median, months [96%CL] | OS, median, months [96%CL] | ||
---|---|---|---|---|---|---|
Overall study population N = 42a | 12 (29.3%) | 31 (75.6%) | 6 (14.3%) | 8.0 [5.8–10.1] | 15.1 [13.0–17.2] | |
Primary tumor location | Intrahepatic CCA n = 21a | 3 (15.0%) | 14 (70.0%) | 1 (4.8%) | 6.9 [4.1–9.8] | 15.3 [8.8–21.7] |
Other locations n = 21 | 9 (42.9%) | 17 (81.0%) | 5 (23.8%) | 11.7 [4.1–19.2] | 15.1 [13.0–17.2] | |
p-value | 0.050 | 0.484 | 0.184 | 0.005 | 0.492 | |
Disease extension | Locally advanced n = 10 | 3 (30.0%) | 8 (80.0%) | 3 (30.0%) | 4.7 [1.1–8.3] | 9.1 [0–19.2] |
Metastatic n = 32a | 9 (29.0%) | 23 (74.2%) | 3 (9.4%) | 9.5 [7.1–11.9] | 15.1 [13.2–17.0] | |
p-value | 1 | 1 | 0.135 | 0.479 | 0.932 |