Skip to main content
Fig. 2 | BMC Cancer

Fig. 2

From: Clinical association of progesterone receptor isoform A with breast cancer metastasis consistent with its unique mechanistic role in preclinical models

Fig. 2

Relationships among total PR, PR-A, PR-B and ER and their associations with lymph node status. Scatter plots of total PR vs. PR-A (Panel a), PR-B vs. PR-A (Panel b), and ER vs. PR-A (Panel c). In Panels A-C, the relative gene expression values are represented after Box-Cox transformation. The solid line represents the linear regression line. The correlation coefficients (r) in repeated measures were estimated using linear mixed-effects models. Associations between lymph node status versus total PR (Panel d), PR-A (Panel e), PR-B (Panel f), PR-A/PR-B (Panel g), and ER (Panel h). In Panels D-H, the relative gene expression values are represented after Box-Cox transformation. The solid lines represent the overall mean values. The associations in repeated measures were assessed using a linear mixed-effects model. The transformed expression levels in each group were summarized by mean and standard error of mean (SEM). The fold change (lymph node positive vs. negative) was calculated using the medians of raw expression levels

Back to article page