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Table 1 Clinicopathological features of 118 cases diagnosed with DCIS by preoperative biopsy

From: Factors predictive of invasive ductal carcinoma in cases preoperatively diagnosed as ductal carcinoma in situ

Parameters

Number of patients (n = 118) (%)

Age at operation (years old)

51 (30–78)

Symptoms

 Asymptomatic / Symptomatic

42 (35.6%) / 76 (64.4%)

Palpability

 Impalpabe / Palpable

33 (28.0%) / 85 (72.0%)

Tumor size (mm)

17.7 (3.0–50.0)

Biopsy device

 Core needle biopsy / Vacuum-assisted biopsy

67 (56.8%) / 51 (43.2%)

Estrogen receptor

 Negative / Positive

22 (18.6%) / 96 (81.4%)

Progesterone receptor

 Negative / Positive

37 (31.4%) / 81 (68.6%)

HER2

  ≤ 2 / 3

101 (85.6%) / 17 (14.4%)

Ki67

  ≤ 14% / > 14%

98 (83.1%) / 20 (16.9%)

Grade of DCIS

 

 Low, intermediate / High

98 (83.1%) / 20 (16.9%)

Comedonecrosis

 Absence / Presence

54 (45.8%) / 64 (54.2%)

Intraductal calcification

 Absence / Presence

99 (83.9%) / 19 (16.1%)

Lymphoid infiltrate

 Negative, mild / moderate, severe

83 (70.3%) / 35 (29.7%)

Postoperative pathology

 DCIS only / Invasive ductal carcinoma

70 (59.3%) / 48 (40.7%)

Platelets–lymphocyte ratio

median 138.9 (range, 55.0–292.0)

 Low / High

70 (59.3%) / 48 (40.7%)

LDH

median 170 (range, 121–452)

  ≤ ULN / >ULN

105 (89.0%) / 13 (11.0%)

CEA

median 1.6 (range, < 0.5–12.4)

  ≤ ULN / >ULN

111 (94.1%) / 7 (5.9%)

CA15–3

median 6.6 (range, < 0.5–40.8)

  ≤ ULN / >ULN

115 (97.5%) / 3 (2.5%)

  1. DCIS Ductal carcinoma in situ, HER2 Human epidermal growth factor receptor 2, LDH Lactate dehydrogenease, CEA Carcinoembryonic antigen, ULN Upper limit of normal