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Table 1 Clinico-pathological features of “Triple Negative” breast cancer

From: Histologic subtyping affecting outcome of triple negative breast cancer: a large Sardinian population-based analysis

Variables

TNBC n (%)

(n = 1009)

n (%)

Age

  < 35

47 (4.7)

 35–49

263 (26.1)

 50–69

503 (49.9)

 70+

195 (19.3)

 Missing

1

Site

 Right

429 (48.6)

 Left

447 (50.7)

 Bilateral

6 (0.7)

 Missing

127

Histologic type

 IBC-NST

745 (78.1)

 Lobular

62 (6.5)

 Mucinous

2 (0.2)

 Medullary

39 (4.1)

 Mixed IBC-NST and invasive lobular

7 (0.7)

 Apocrine

43 (4.5)

 Papillary

7 (0.7)

 Adenoid cystic

6 (0.6)

 Metaplastic

42 (4.4)

 Micropapillary

2 (0.2)

 Missing

54

Histologic grade

 G1

11 (1.1)

 G2

204 (21.3)

 G3

744 (77.6)

 Missing

50

Tumor size

 pT0

1 (0.1)

 pT1

379 (40.6)

 pT2

441 (47.3)

 pT3

59 (6.3)

 pT4

53 (5.7)

 Missing

76

Lymph node status

 pN0

533 (59.4)

 pN1

214 (23.9)

 pN2

90 (10.0)

 pN3

60 (6.7)

 Missing

112

Metastasis

 M0

812 (95.8))

 M1

36 (4.2

 Missing

161

TNM stage

 I

258 (29.1)

 II

413 (46.5)

 III

182 (20.5)

 IV

35 (3.9)

 Missing

121

Lymph node ratio

  < 0,2

717 (81.4)

 0,21-0,65

103 (11.7)

  > 0,65

61 (6.9)

 Missing

128

Lymphovascular invasion

 yes

349 (45.0)

 no

427 (55.0)

 Missing

233

Necrosis

 Present

491 (61.0)

 Absent

314 (39.0)

 Missing

184

Lymphocytic infiltrate

 yes

504 (64.5)

 no

278 (35.5)

 Missing

227

Proliferation index (Ki-67)

  < 14%

94 (9.9)

 15–30%

155 (16.4)

  ≥ 30%

698 (73.7)

 Missing

62

Androgen Receptor

 Positive

125 (24.3)

 Negative

389 (75.7)

 Missing

495

Type of surgery

 Mastectomy

341 (42.2)

 Quadrantectomy

451 (55.5)

 Lumpectomy

17 (2.0)

 Missing

200

Adjuvant chemotherapy

 yes

580 (57.5)

 no

429 (42.5)

Adjuvant radiotherapy

 yes

364 (36.1)

 no

645 (63.9)

Recurrence

 yes

67 (6.6)

 no

942 (93.4)

Contralateral breast cancer

 yes

69 (6.8)

 no

940 (93.2)

  1. n = number