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Fig. 1 | BMC Cancer

Fig. 1

From: LGR5 in breast cancer and ductal carcinoma in situ: a diagnostic and prognostic biomarker and a therapeutic target

Fig. 1

LGR5 and clinicopathological features in BC. a Representative images of LGR5-stained primary human BC (numbers on bottom left of each image indicate score for tumor staining intensity). Scale bar, 50 μM. b Analysis of patient samples in METABRIC database for LGR5 expression in >ER− vs. ER+ BC show elevated LGR5 expression in ER− BC. c Various BC subtypes with Basal BC showing a statistically significant elevation in LGR5 expression compared to Luminal A, Luminal B, and Her2, mean ± SEM. (Student t-test, ***P < 0.001, ****P < 0.0001)

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