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Fig. 4 | BMC Cancer

Fig. 4

From: Up-regulation of GLI1 in vincristine-resistant rhabdomyosarcoma and Ewing sarcoma

Fig. 4

Gene expression changes in VCR-resistant RMS and EWS cells compared with parental cells by PCR array. a Rh30VR cells showed significant changes (at least 2-fold up-regulated or down-regulated, and p ≤ 0.05) in gene expression in 30 genes, including GLI1, that were included in the 86 gene drug resistance panel compared with parental cells. The experiment was completed in triplicate. Averages (bars) and standard deviations (brackets) are shown. * indicates p ≤ 0.05 and fold change is indicated on the y-axis. b Rh41VR cells showed significant changes (at least 2-fold up-regulated or down-regulated, and p ≤ 0.05) in gene expression in 35 genes, including GLI1, that were included in the 86 gene drug resistance panel compared with the parental cells. The experiment was completed in triplicate. Averages (bars) and standard deviations (brackets) are shown. * indicates p ≤ 0.05 and fold change is indicated on the y-axis. c TC71VR cells showed significant changes (at least 2-fold up-regulated or down-regulated, and p ≤ 0.05) in gene expression in 12 genes, including GLI1, that were included in the 86 gene drug resistance panel compared with the parental cells. The experiment was completed in triplicate. Averages (bars) and standard deviations (brackets) are shown. * indicates p ≤ 0.05 and fold change is indicated on the y-axis. Microsoft Exel and Adobe Photoshop were used to prepare Figure 4

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