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Table 3 Patient Characteristics by ALK Rearrangement Status

From: Frequency of anaplastic lymphoma kinase rearrangements in Moroccan patients with non small cell lung cancer: a multi-institutional national retrospective study

CharacteristicsALK Rearrangement Status N(%)P
NegativePositive
Total115 (95.8%)5 (4.2%) 
Mean age at diagnosis (yr)63.367.8<0.0001*
Gender  0.58**
 Male87 (75.7%)5 (100%) 
 Female28 (24.3%)0 (0%) 
Smoking history  0.65**
 Smoker66 (57.4%)2 (40%) 
 Non-smoker49 (42.6%)3 (60%) 
Histological type  0.50**
 Adenocarcinoma100 (87%)5 (100%) 
 Others15 (13%)0 (0%) 
ALK test  0.09**
 FISH88 (76.5%)2 (40%) 
 IHC27 (23.5%)3 (60%) 
EGFR status  0.58**
 Mutated21 (100%)0 (0%) 
 Wild94 (94.9%)5 (5.1%) 
Kras status  0.69**
 Mutated7 (100%)0 (0%) 
 Wild52 (94.5%)3 (5.5%) 
  1. *p value calculated by t test
  2. **p value calculated by Fisher’s exact test
  3. ALK anaplastic lymphoma kinase, FISH fluorescent in situ hybridization, IHC immunohistochemistry, EGFR epidermal growth factor receptor, Kras Kirsten rat sarcoma