Table 3 Patient Characteristics by ALK Rearrangement Status
Characteristics | ALK Rearrangement Status N(%) | P | |
|---|---|---|---|
Negative | Positive | ||
Total | 115 (95.8%) | 5 (4.2%) | |
Mean age at diagnosis (yr) | 63.3 | 67.8 | <0.0001* |
Gender | 0.58** | ||
Male | 87 (75.7%) | 5 (100%) | |
Female | 28 (24.3%) | 0 (0%) | |
Smoking history | 0.65** | ||
Smoker | 66 (57.4%) | 2 (40%) | |
Non-smoker | 49 (42.6%) | 3 (60%) | |
Histological type | 0.50** | ||
Adenocarcinoma | 100 (87%) | 5 (100%) | |
Others | 15 (13%) | 0 (0%) | |
ALK test | 0.09** | ||
FISH | 88 (76.5%) | 2 (40%) | |
IHC | 27 (23.5%) | 3 (60%) | |
EGFR status | 0.58** | ||
Mutated | 21 (100%) | 0 (0%) | |
Wild | 94 (94.9%) | 5 (5.1%) | |
Kras status | 0.69** | ||
Mutated | 7 (100%) | 0 (0%) | |
Wild | 52 (94.5%) | 3 (5.5%) | |