Fig. 3
From: Prognostic impact of Dynamin related protein 1 (Drp1) in epithelial ovarian cancer
Kaplan-Meier survival curves for progression-free survival and overall survival rates among patients with epithelial ovarian cancer according to IRS-score of Drp1, phospho-Drp1Ser637, and CaMKI. a PFS in patients with high IRS-score of Drp1 (≥10.5, solid line) and low IRS-score of Drp1 (< 10.5, dotted line). Patients with high IRS-score of Drp1 showed poorer PFS (p = 0.003) compared with patients with low IRS-score of Drp1. b PFS in patients with high IRS-score of phospho-Drp1Ser637 (≥7.0, solid line) and low IRS-score of phospho-Drp1Ser637 (< 7.0, dotted line). Patients with high IRS-score of phospho-Drp1Ser637 showed poorer PFS (p < 0.001) than patients with low IRS-score of phospho-Drp1Ser637. c PFS in patients with high IRS-score of CaMKI (≥10.5, solid line) and low IRS-score of CaMKI (< 10.5, dotted line). Patients with high IRS-score of CaMKI showed poorer PFS (p = 0.017) than patients with low IRS-score of CaMKI. d OS in patients with high IRS-score of Drp1 (≥10.5, solid line) and low IRS-score of Drp1 (< 10.5, dotted line). No differences in OS is apparent according to IRS-score of Drp1. e OS in patients with high IRS-score of phospho-Drp1Ser637 (≥7.0, solid line) and low IRS-score of phospho-Drp1Ser637 (< 7.0, dotted line). No differences in OS is apparent according to IRS-score of phospho-Drp1Ser637. f OS in patients with high IRS-score of CaMKI (≥10.5, solid line) and low IRS-score of CaMKI (< 10.5, dotted line). Patients with high IRS-score of CaMKI show poorer OS (p = 0.030) than patients with low IRS-score of CaMKI