Incidence of subsequent primary cancers and radiation-induced subsequent primary cancers after low dose-rate brachytherapy monotherapy for prostate cancer in long-term follow-up

Table 2 Metachronous SPCs, time to SPCs and locations of the SPCs after LDR-BT

SPCs, organs involved	n	%	< 5 years	≥ 5 years	OOF	IF
All	36	100	13	23	32	4
Lung	6	16.7	2	4	6
Colon	5	13.9	2	3	5
Skin^a	5	13.9	3	2	5
Hematologic	4	11.1	3	1	4
Bladder	2	5.6		2		2
Rectum	1	2.8		1		1
Prostate (SCC)	1	2.8		1		1
Other^b	12	33.3	3	9	12

SPC Subsequent primary cancer, LDR-BT Low dose-rate brachytherapy, SCC Squamous cell cancer, OOF Out-of-field, IF In-field
^aFibrosarcoma, Squamous cell cancer, Melanoma
^bHead and neck (n = 3), Liver (n = 2) and one of each: Brain, Eye melanoma, Esophagus, Pancreas, Kidney, Malignant schwannoma (muscle), Sarcoma (hand)

ISSN: 1471-2407