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Fig. 1 | BMC Cancer

Fig. 1

From: Exploratory analysis of immune checkpoint receptor expression by circulating T cells and tumor specimens in patients receiving neo-adjuvant chemotherapy for operable breast cancer

Fig. 1

Representative flow cytometry plots demonstrating gating strategy to identify CD4+ and CD8+ T cells as well as expression of various immune checkpoint receptors. (a) Representative scatter plots to show gating for CD4+ and CD8+ T cells. (b) Histograms of isotype controls are shown in gray and checkpoint receptor (CTLA4, Lag3, OX40, PD-1, and Tim3) expressions are shown in blue. Positive measurement of each checkpoint receptor is demonstrated within brackets. (c) Representative histograms for pre-NAC (blue) and post-NAC (red) checkpoint receptor expression are shown

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BMC Cancer

ISSN: 1471-2407

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