Skip to main content
Fig. 3 | BMC Cancer

Fig. 3

From: Acquired resistance to DZNep-mediated apoptosis is associated with copy number gains of AHCY in a B-cell lymphoma model

Fig. 3

AHCY copy number gain in the DZNep-resistant clone: chromosomal and transcriptional validation. a FISH analysis using AHCY target-specific probes in the resistant clone and its control. Yellow arrows show in pink color a cluster-type amplification of AHCY. Green dots represent the centromere of chromosome 20. b Transcriptional expression of AHCY. cDNA was synthesized from the RNA of all cell lines. Relative gene expression (shown on the y-axis) was quantified using the AHCY gene expression assay, with B2M and SDHA used as an endogenous control. RQ is shown as mean plus SD of triplicate measurements

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us