Table 3 Detection of histologic high-grade squamous intraepithelial lesion or worse lesions by different hrHPV genotyping approaches in the study population
No. of hrHPV positive women with normal cytology and with availble histologic or colposcopic results | No. of histologic HSIL+ | Percentage of HSIL+ detected, n = 204 | Ratio of colposcopy per HSIL+ detection | OR | 95% CI | P value | |
|---|---|---|---|---|---|---|---|
HPV16 | 801 | 119 | 58.3 | 6.7 | 3.75 | 2.79–5.05 | < 0.001 |
HPV18 | 206 | 12 | 5.9 | 17.2 | 0.72 | 0.39–1.32 | 0.29 |
HPV31 | 142 | 15 | 7.4 | 9.5 | 1.46 | 0.83–2.57 | 0.19 |
HPV33 | 187 | 22 | 10.8 | 8.5 | 1.69 | 1.04–2.72 | 0.03 |
HPV52 | 362 | 28 | 13.7 | 12.9 | 1.03 | 0.68–1.57 | 0.90 |
HPV58 | 414 | 26 | 12.7 | 15.9 | 0.78 | 0.51–1.20 | 0.26 |
HPV16/18 | 992 | 129 | 63.2 | 7.7 | 3.26 | 2.41–4.40 | < 0.001 |
HPV16/18/33 | 1162 | 148 | 72.5 | 7.9 | 3.85 | 2.79–5.31 | < 0.001 |
HPV16/18/31/33 | 1282 | 158 | 77.5 | 8.1 | 4.21 | 2.99–5.93 | < 0.001 |
HPV16/18/31/33/52/58 | 1938 | 190 | 93.1 | 10.2 | 5.73 | 3.30–9.97 | < 0.001 |