Clinical value of serum squamous cell carcinoma antigen levels in predicting chemosensitivity, lymph node metastasis, and prognosis in patients with cervical squamous cell carcinoma

Table 2 Correlation analysis of SCC antigen levels with clinical characteristics of patients with cervical squamous cell carcinoma

Clinical characteristics		Conventional group	NACT group
Clinical characteristics		SCC antigen	ISCC	SSCC	OSCC	FSCC	TSCC	FSCC (%)	TSCC (%)
Age	Spearman CC	0.204	0.064	0.095	0.134	0.073	0.037	0.102	0.057
Age	P value	0.220	0.616	0.457	0.295	0.565	0.774	0.421	0.655
Tumor differentiation degree	Spearman CC	0.076	0.111	0.195	0.117	0.109	0.158	−0.016	0.126
Tumor differentiation degree	P value	0.644	0.381	0.123	0.359	0.389	0.212	0.903	0.323
Number of positive lymph nodes	Spearman CC	0.673	0.326	0.436	0.395	0.237	0.274	0.060	0.089
Number of positive lymph nodes	P value	< 0.001	0.009	< 0.001	0.001	0.059	0.029	0.637	0.484
Maximum length of the lesion before chemotherapy	Spearman CC	0.643	0.352	0.217	0.212	0.429	0.402	0.383	0.283
Maximum length of the lesion before chemotherapy	P value	< 0.001	0.004	0.085	0.096	< 0.001	0.001	0.002	0.023
Maximum length of the lesion after chemotherapy	Spearman CC	–	0.046	0.142	0.183	0.019	0.040	−0.020	−0.075
Maximum length of the lesion after chemotherapy	P value	–	0.718	0.263	0.151	0.880	0.754	0.874	0.558
Narrowing extent of the lesion	Spearman CC	–	0.326	0.083	0.003	0.413	0.391	0.387	0.424
Narrowing extent of the lesion	P value	–	0.008	0.515	0.980	0.001	0.001	0.002	<0.001
Survival time	Spearman CC	−0.060	−0.154	−0.263	−0.265	−0.086	− 0.030	0.033	0.111
Survival time	P value	0.716	.0.227	0.037	0.037	0.502	0.816	0.800	0.387

CC Correlation Coefficient, SCC antigen Squamous cell carcinoma antigen, ISCC The SCC antigen level before the first chemotherapy, SSCC The SCC antigen level after the first chemotherapy, OSCC The SCC antigen level after the second chemotherapy, FSCC The absolute value of the decreased SCC antigen level after the first chemotherapy, TSCC The absolute value of the decreased SCC antigen level after total chemotherapy, FSCC (%) Percentage decrease in SCC antigen level after the first chemotherapy, TSCC (%) Percentage decrease in SCC antigen level after total chemotherapy

ISSN: 1471-2407