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Table 2 Basic features of studies for diagnosis analysis

From: Prognostic and diagnostic value of circRNA expression in colorectal carcinoma: a meta-analysis

 

Sample size

 

Diagnosis power

Study

Year

CircRNA

Cancer Type

case

control

Method

Regulation

Sen.

Spe.

AUC.

Ji et al. [16]

2018

circ_0001649

CRC

64

64

qRT-PCR

downregulated

0.828

0.781

0.857

Li et al. [19]

2018

circITGA7

CRC

69

48

qRT-PCR

downregulated

0.928

0.667

0.879

Wang et al. [24]

2017

circ_0000567

CRC

102

102

qRT-PCR

downregulated

0.833

0.765

0.865

Zhuo et al. [28]

2017

circ_0003906

CRC

122

40

qRT-PCR

downregulated

0.803

0.725

0.818

Ruan et al. [22]

2019

circ_0002138

CRC

35

35

qRT-PCR

downregulated

0.629

0.743

0.725

Wang et al. [32]

2015

circ_001988

CRC

31

31

qRT-PCR

downregulated

0.680

0.730

0.788

Li et al. [18]

2018

circ_0000711

CRC

101

101

qRT-PCR

downregulated

0.910

0.58

0.810

  1. AUC Area under the ROC curve; qRT-PCR Quantitative real-time polymerase chain reaction; Sen Sensitivity; Spe. Specificity; CRC Colorectal cancer