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Table 3 Comparison of polymorphisms between colorectal cancer patients and controls

From: Association of DNA repair gene variants with colorectal cancer: risk, toxicity, and survival

  Total, n (%) Patients, n (%) Controls, n (%) Odds ratio (95% confidence interval) p
XRCC1-rs25487
 G/G 381 (42.8) 253 (42.9) 128 (42.7)   
 G/A + A/A 509 (57.2) 337 (57.1) 172 (57.3) 1.0 (0.7–1.3) 0.95
ERCC1-rs11615
 T/T 359 (40.8) 237 (40.9) 122 (40.7)   
 C/T + C/C 521 (59.2) 343 (59.1) 178 (59.3) 1.0 (0.7–1.3) 0.95
ERCC2-rs238406
 C/C 248 (28.5) 178 (31.1) 70 (23.6)   
 C/A + A/A 621 (71.5) 394 (68.9) 227 (76.4) 1.5 (1.1–2.0) 0.01
ERCC2-rs13181
 A/C + C/C 518 (59.2) 362 (62.3) 156 (53.1)   
 A/A 357 (40.8) 219 (37.7) 138 (46.9) 1.4 (1.0–1.9) 0.009
ERCC2-rs238406 AND ERCC2-rs13181
 Unfavourable: [ERCC2-rs238406 C/C] AND [ERCC2-rs13181 A/C + C/C] 227 (25.3) 172 (28.9) 55 (18.2)   
 Favourable: [ERCC2-rs238406 C/A + A/A] AND/OR [ERCC2-rs13181 A/A] 670 (74.7) 424 (71.1) 246 (81.7) 1.8 (1.3–2.6) 0.001