Table 2 Genotype distributions in colorectal cancer patients and healthy controls
From: Association of DNA repair gene variants with colorectal cancer: risk, toxicity, and survival
Gene | Group | Rs number | Locus/effect | Major homozygote | Heterozygote | Minor homozygote | Total n | Hardy-Weinberg p |
|---|---|---|---|---|---|---|---|---|
XRCC1 | Patients | rs25487 | Arg399Gln | 253 (G/G) | 269 (G/A) | 68 (A/A) | 590 | 0.96 |
| Â | Controls | Â | Â | 128 (G/G) | 136 (G/A) | 36 (A/A) | 300 | 1.0 |
ERCC1 | Patients | rs11615 | Asn118Asn | 237 (T/T) | 265 (C/T) | 78 (C/C) | 580 | 0.96 |
| Â | Controls | Â | Â | 122 (T/T) | 151 (C/T) | 27 (C/C) | 300 | 0.12 |
ERCC2 | Patients | rs238406 | Arg156Arg | 178 (C/C) | 282 (C/A) | 112 (A/A) | 572 | 1.0 |
| Â | Controls | Â | Â | 70 (C/C) | 162 (C/A) | 65 (A/A) | 297 | 0.29 |
ERCC2 | Patients | rs13181 | Lys751Gln | 219 (A/A) | 286 (A/C) | 76 (C/C) | 581 | 0.51 |
| Â | Controls | Â | Â | 138 (A/A) | 125 (A/C) | 31 (C/C) | 294 | 0.94 |