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Table 1 Patient characteristics (n = 596)

From: Association of DNA repair gene variants with colorectal cancer: risk, toxicity, and survival

 

n (%)

Age, mean (± SD) yrs

69.4 (± 12.1)

Gender (Male)

338 (56.7)

Tumor location

 Rectum

251 (42.4)

 Left-sided colon

132 (22.3)

 Right-sided colon

209 (35.3)

Tumor differentiation

 Well

22 (3.7)

 Moderate

423 (71.3)

 Poor

138 (23.3)

 Mucinous

6 (1.0)

Stage

 I

62 (10.4)

 II

203 (34.1)

 III

234 (39.3)

 IV

94 (15.8)

Lymph node count ≥12

413 (69.3)

Positive lymph node

293 (52.1)

Received preoperative radiotherapya

130 (21.7)

Radically operated

509 (86.3)

Received chemotherapyb

236 (39.6)

 Adjuvant therapy

171 (55.1)

 First-line therapy

101 (25.4)

 Confirmed response to therapy

74 (78.7)

Relapsed

160 (32.1)

Status at last follow-up

 Dead

362 (60.7)

 Alive

231 (38.8)

  1. NOTE- Unknown data: Tumor location for 4 patients; Tumor differentiation for 7 patients; Tumor stage for 3 patients; Radical operation for 6 patients; relapse for 1 patient, status at last follow-up for 3 patients. aOnly for rectal cancer patients; b 41 patients had both adjuvant and first-line therapy, response to therapy was measured only for 94 patients who had undergone first-line therapy