Fig. 3

Gene co-expression modules correlated with platinum-based chemotherapy response. a Network plot displaying the five significant gene co-expression modules from WGCNA: honeydew1 - centre, lightcyan1 - left, lightpink3 - top, orangered4 - bottom, and skyblue3 - right. Nodes represent probes and edges are connections among the probes. Co-expressed probes (i.e. belonging to a single module) are indicated by the same color. b Heatmap demonstrating the association strength between the expression of gene modules and chemoresistance phenotype. Significance (p-value) of module-trait association is displayed beside each module. Colors represent strength of correlation, where red color indicates higher expression in chemoresistance population and green indicate higher expression in sensitive population. This figure was generated using Cytoscape (v.3.7.0)