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Fig. 2 | BMC Cancer

Fig. 2

From: Gene networks and expression quantitative trait loci associated with adjuvant chemotherapy response in high-grade serous ovarian cancer

Fig. 2

Kaplan-Meier (KM) plot of an independent ovarian cancer cohort for cross-validation of differentially expressed gene VCP and gene modules. KM plot shows the Progression-Free Survival (PFS) of the replication ovarian cancer cohort post platinum-based chemotherapy treatment. (A) shows the PFS of patients with high/low VCP expression, while (B) shows PFS of patients with high/low module-wide expression for (i) honeydew1, (ii) lightcyan1, (iii) lightpink3, (iv) orangered4, (v) skyblue3 modules. Red line in (A) indicates the PFS of patients with high VCP expression and black line indicates the PFS of patients with low VCP or module expression. Patients with high expression of VCP are associated with better PFS with statistical significance. Green line in (B) indicates the PFS of patients with high module-wide expression and red line indicates PFS of patients with low module-wide expression. Similarly, patients with high module wide expression are associated with better PFS with statistical significance. This figure was generated using the web-interface of the Kaplan-Meier Plotter and survExpress

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