Table 1 Baseline characteristics
| Â | GNRI/sarcopenia risk | P | |
|---|---|---|---|
High cachexia risk (n = 71) | Low cachexia risk (n = 157) | ||
Median age (range), years | 70 (27–88) | 59 (21–86) | <  0.001 |
  ≤ 60 | 13 (18.3) | 83 (52.9) | <  0.001 |
  > 60 | 58 (81.7) | 74 (47.1) |  |
Sex | Â | Â | 0.111 |
 Male | 46 (64.8) | 84 (53.5) |  |
 Female | 25 (35.2) | 73 (46.5) |  |
ECOG PS |  |  | <  0.001 |
 0–1 | 33 (46.5) | 131 (83.4) |  |
 2–3 | 38 (53.5) | 26 (16.6) |  |
B-symptoms |  |  | <  0.001 |
 Absent | 46 (64.8) | 138 (87.9) |  |
 Present | 25 (35.2) | 19 (12.1) |  |
Bulky disease | Â | Â | 0.009 |
 Non-bulky | 52 (73.2) | 137 (87.3) |  |
 Bulky | 19 (26.8) | 20 (12.7) |  |
Ann Arbor stage |  |  | <  0.001 |
 I – II | 17 (23.9) | 83 (52.9) |  |
 III – IV | 54 (76.1) | 74 (47.1) |  |
Extranodal disease | Â | Â | 0.007 |
 Absent | 17 (23.9) | 67 (42.7) |  |
 Present | 54 (76.1) | 90 (57.3) |  |
LDH | Â | Â | 0.005 |
 Normal | 19 (26.8) | 73 (46.5) |  |
 Elevated | 52 (73.2) | 84 (53.5) |  |
IPI |  |  | <  0.001 |
 Low to Low-intermediate | 19 (26.8) | 107 (68.2) |  |
 High-intermediate to High | 52 (73.2) | 50 (31.9) |  |
NCCN-IPI |  |  | <  0.001 |
 Low to Low-intermediate | 11 (15.5) | 95 (60.5) |  |
 High-intermediate to High | 60 (84.5) | 62 (39.5) |  |
Cell-of-origin (n = 135) |  |  | 0.421 |
 GCB | 10 (23.3) | 16 (17.4) |  |
 Non-GCB | 33 (76.7) | 76 (82.6) |  |
Median BMI (range), kg/m2 | 21.7 (15.6–29.8) | 23.9 (15.1–33.7) | <  0.001 |