Total | < 3 mutations (n = 97) | ≥ 3 mutations (n = 69) | P value | |
---|---|---|---|---|
Gender | p > 0.05 | |||
Male | 72 | 44 | 28 | |
Female | 94 | 53 | 41 | |
Age | 32–91 | 33–91 | 32–88 | |
Location | p > 0.05 | |||
Cecum | 38 | 14 | 24 | |
Ascending colon | 34 | 19 | 15 | |
Transverse colon | 18 | 11 | 7 | |
Descending | 8 | 4 | 4 | |
Sigmoid colon | 38 | 29 | 9 | |
Rectum | 30 | 20 | 10 | |
Histologic grade | p = 0.0010 | |||
Low | 126 | 82 | 43 | |
High | 40 | 15 | 26 | |
Pathologic stage | p > 0.05 | |||
T1 | 7 | 4 | 3 | |
T2 | 10 | 6 | 4 | |
T3 | 97 | 57 | 40 | |
T4 | 52 | 30 | 22 | |
Positive lymph nodes | p > 0.05 | |||
Yes | 99 | 62 | 37 | |
No | 67 | 35 | 32 | |
MSI status | P > 0.05 | |||
MSI-proficient | 124 | 76 | 48 | |
MSI-deficient | 42 | 21 | 21 | |
CRC without mucinous differentiation | 117 | 72 | 45 | P < 0.01 |
Low grade | 85 | 59 | 26 | |
High grade | 32 | 13 | 19 |