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Table 1 The association between mutation genes number and clinicopathologic features

From: Colorectal carcinomas with mucinous differentiation are associated with high frequent mutation of KRAS or BRAF mutations, irrespective of quantity of mucinous component

 

Total

< 3 mutations (n = 97)

≥ 3 mutations (n = 69)

P value

Gender

   

p > 0.05

Male

72

44

28

 

Female

94

53

41

 

Age

32–91

33–91

32–88

 

Location

   

p > 0.05

Cecum

38

14

24

 

Ascending colon

34

19

15

 

Transverse colon

18

11

7

 

Descending

8

4

4

 

Sigmoid colon

38

29

9

 

Rectum

30

20

10

 

Histologic grade

   

p = 0.0010

Low

126

82

43

 

High

40

15

26

 

Pathologic stage

   

p > 0.05

T1

7

4

3

 

T2

10

6

4

 

T3

97

57

40

 

T4

52

30

22

 

Positive lymph nodes

   

p > 0.05

Yes

99

62

37

 

No

67

35

32

 

MSI status

   

P > 0.05

MSI-proficient

124

76

48

 

MSI-deficient

42

21

21

 

CRC without mucinous differentiation

117

72

45

P < 0.01

Low grade

85

59

26

 

High grade

32

13

19