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Table 1 Demographic and clinical data of patients (n = 88)

From: Evaluation of adverse effects of chemotherapy regimens of 5-fluoropyrimidines derivatives and their association with DPYD polymorphisms in colorectal cancer patients

Age; year

 Mean

58.7

 SD

12.9

Sex; number (%)

 Male

48 (54.5)

 Female

40 (45.5)

Site of Cancer; number(%)

 Colon

64 (72.7)

 Rectum

24 (27.3)

Tumor stage; number(%)

 Stage 2a

9 (12.3)

 Stage 2b

8 (11)

 Stage 2c

3 (4.1)

 Stage 3a

3 (4.1)

 Stage 3b

14 (19.2)

 Stage 3c

6 (8.2)

 Stage 4a

25 (34.2)

 Stage 4b

5 (6.9)

Chemotherapy; number of cycles(%)

 FOLFOX

165 (72.7)

 FOLFIRI

47(20.7%)

 Capecitabine + Cetuximab

3 (1.3)

 Capecitabine

6 (2.7)

 FOLOFOX-IRI

5 (2.2)

 5-FU

1 (0.4)

  1. 5-FU 5-Fluorouracil, FOLFOX: 5-FU leucovorin and oxaliplatin, FOLFIRI: 5-FU leucovorin and irinotecan; colorectal cancer TNM staging was accordant to the American Joint Committee on Cancer staging manual (8th edition)