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Fig. 1 | BMC Cancer

Fig. 1

From: FAT4 silencing promotes epithelial-to-mesenchymal transition and invasion via regulation of YAP and β-catenin activity in ovarian cancer

Fig. 1

a. Relative expression of FAT4 at mRNA levels in ovarian cancer cell lines. MCAS and OVSAHO show high FAT4 expression as compared to A2780 and A2780 cis (p = 0.0001). b. Relative expression of FAT4 at protein levels in MCAS and OVSAHO cells. FAT4 was highly expressed in OVSAHO (p = 0.0459), and MCAS (p = 0.0107), cells while, it was least expressed in A2780 cis (p = 0.006) and A2780 (p = 0.0012) cells. Full-length blots are presented in Supplementary figure S1. c. Differential expression of FAT4 in tumor and healthy ovarian tissue sample from GEPIA database. FAT4 was significantly downregulated in 426 tumor samples as compared to 87 healthy samples. Red line represents tumor samples and green line represents healthy ovarian samples. Data represent mean and standard deviation from at least three independent experiments performed in triplicates

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