Fig. 6
From: Prdx1 promotes the loss of primary cilia in esophageal squamous cell carcinoma
Inhibition of Prdx1 decreased tumorigenesis, reduced tumor volume and weight, and promoted cilia regeneration. a Live imaging was used to detect the tumorigenesis, and the radiant efficiency and distribution of luciferase luminescence were used as indicators of tumor formation ability and tumor invasive capacity, respectively. b The radiant efficiency of luciferase luminescence in each group. c Changes of tumor weight after inhibition of Prdx1. d-e Changes of tumor volume in each group. f Immunofluorescence assay to detect the cilium marker protein (red: acetyl-α-tubulin, blue: DAPI, white arrows: cilia) in tumor tissue of each group. g Changes in the number of cells with cilia (%) in tumor tissue of each group. *P < 0.05, **P < 0.01, ***P < 0.001