Fig. 7
RA190 treatment inhibited the growth of orthotopic HCC tumor model. a Bioluminescence imaging showing the HepG2 tumors following orthotopic challenge with HepG2-Luc cells (5 × 105 /mouse) administered in the left lobe of liver of nude mice. Mice were treated with either DMSO or RA190 (20 mg/kg) once daily via the intra peritoneal route beginning at day 7 and ending at day 28. Imaging of bioluminescence after injection of luciferin via the intraperitoneal route was performed on an IVIS 200 imager and the data plotted b. Bioluminescence was significantly different (P < 0.02) between the groups on day 42