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Table 6 Characteristics of 6 locally advanced patients with resection

From: Neoadjuvant chemotherapy followed by curative-intent surgery for perihilar cholangiocarcinoma based on its anatomical resectability classification and lymph node status

No

Age

(years)

Gender

Factor of unresectability

Adjuvant

chemotherapy

Adjuvant

radiotherapy

Type of ***

Hepatectomy

Vascular

resection

pLN

Residual

tumor

Survival

(status)

1)

50’s

F

Biliary*

G (3 cycles)

36Gy

S1,4,5,6,7,8

PV

1

R2

22.5 m (Dead)

2)

80’s

M

Biliary*

GS (2 cycles)

–

S1,5,6,7,8

–

1

R0

8.8 m (Dead)

3)

60’s

M

Biliary*

GS (2 cycles) +

GC (4 cycles)

36Gy

S1,2,3,4

PV

0

R1

49.4 m (Dead)

4)

50’s

M

Biliary*

GS (2 cycles)

–

S1,5,6,7,8

PV

1

R0

47.0 m (Alive)

5)

70’s

F

Vascular (HA)**

GS (10 cycles)

–

S1,5,6,7,8

–

0

R0

49.5 m (Alive)

6)

60’s

M

Vascular (HA)**

GS (4 cycles)

–

S1,2,3,4

HA

0

R0

30.4 m

(Alive)

  1. *Biliary factor: biliary margin negative could not be obtained by either side of right or left trisectionectomy
  2. **Vascular factor: Unreconstructible HA and/or PV due to tumor involvement or occlusion
  3. *** Expressed as Couinoud’s hepatic segments resected
  4. G gemcitabine, GS gemcitabine + TS-1, GC gemcitabine + cisplatin, PV portal vein, HA hepatic artery, LN lymph node, R1 microscopic residual tumor resection, R2 macroscopic residual tumor resection or distant metastasis (intrahepatic metastasis)