Fig. 5From: Neoadjuvant chemotherapy followed by curative-intent surgery for perihilar cholangiocarcinoma based on its anatomical resectability classification and lymph node statusComparison of DSS curves in resected patients based on the preoperative CEA and pT stage. (a) There was significant difference of 5-year DSS between resected patients with preoperative low CEA levels (< 8.5 ng/mL) and high CEA levels (8.5 ng/mL and more) (p < 0.001). Seven patients with preoperative high CEA levels were classified as R (n = 4) and BR (n = 3). (b) There was significant difference of 5-year DSS between patients with pT1–3 and pT4 (p = 0.001). The resected patients with preoperative high CEA levels (more than 8.5 ng/ml) and / or pT4 were no significant differences of DSS compared to unresected patients. DSS: disease-specific survival, R: resectable, BR: borderline resectable, LA: locally advanced, CEA: carcinoembryonic antigen, MST: median survival timeBack to article page