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Table 4 QoL Score as predictor for TTPd (univariate and multivariate analyse)

From: Primary surgery versus no surgery in synchronous metastatic breast cancer: patient-reported quality-of-life outcomes of the prospective randomized multicenter ABCSG-28 Posytive Trial

 

Univariate Analyse

Multivariate Analyse

 

HR

95%-LL

95%-UL

Cox P-value

HR

95%-LL

95%-UL

Cox P-value

Physical Functioning

0.995

0.985

1.006

0.3855

1.006

0.978

1.034

0.6704

Role Functioning

0.995

0.987

1.004

0.2671

1.010

0.988

1.034

0.3741

Emotional Functioning

0.999

0.986

1.011

0.8220

1.018

0.996

1.041

0.1006

Cognitive Functioning

0.993

0.976

1.009

0.3852

1.005

0.979

1.031

0.7245

Social Functioning

0.989

0.979

0.998

0.0140

0.986

0.969

1.003

0.1057

Global health status

0.985

0.973

0.998

0.0244

0.983

0.961

1.005

0.1313

Fatigue

1.003

0.993

1.013

0.6083

1.011

0.988

1.035

0.3465

Nausea / Vomiting

1.010

0.994

1.026

0.2174

1.009

0.978

1.040

0.5811

Pain

1.006

0.998

1.015

0.1443

1.015

0.993

1.037

0.1797

Dyspnoea

1.007

0.996

1.018

0.1908

1.015

0.998

1.032

0.0829

Insomnia

1.000

0.991

1.009

0.9839

0.999

0.986

1.011

0.8211

Appetite loss

1.000

0.990

1.010

0.9466

0.991

0.969

1.013

0.4189

Constipation

0.998

0.987

1.009

0.7022

0.986

0.969

1.003

0.0992

Diarrhoea

0.998

0.983

1.013

0.8056

0.999

0.979

1.018

0.8917

Financial Problems

1.005

0.993

1.016

0.4073

0.998

0.984

1.013

0.8026

BR Body image

0.999

0.985

1.013

0.8986

1.001

0.985

1.017

0.8999

BR Sexual functioning

0.992

0.979

1.006

0.2574

1.001

0.986

1.015

0.9242

BR Future perspective

0.988

0.978

0.999

0.0250

0.982

0.968

0.996

0.0123

BR Systemic therapy

1.000

0.984

1.017

0.9664

1.010

0.984

1.036

0.4762

BR Breast symptoms

1.008

0.994

1.023

0.2611

1.021

1.001

1.041

0.0438

BR Arm symptoms

0.993

0.973

1.012

0.4568

0.994

0.973

1.017

0.6238

BR Hair loss

0.952

0.899

1.010

0.1014

0.933

0.872

0.998

 

BR Sexual enjoyment

1.010

0.984

1.038

0.4525

1.001

0.985

1.017

0.8999

  1. Legends: TTPd- time to distant progression; QoL: Quality of life