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Table 3 QoL Score as predictor for OS (univariate and multivariate analyse)

From: Primary surgery versus no surgery in synchronous metastatic breast cancer: patient-reported quality-of-life outcomes of the prospective randomized multicenter ABCSG-28 Posytive Trial

 

Univariate Analyse

Multivariate Analyse

 

HR

95%-LL

95%-UL

Cox P-value

HR

95%-LL

95%-UL

Cox P-value

Physical Functioning

0.988

0.977

0.999

0.0355

1.016

0.983

1.051

0.3523

Role Functioning

0.993

0.984

1.001

0.0988

0.995

0.969

1.021

0.6966

Emotional Functionin

1.000

0.987

1.014

0.9511

1.031

1.003

1.059

0.0293

Cognitive Functionin

0.999

0.980

1.018

0.9206

0.999

0.961

1.039

0.9723

Social Functioning

0.996

0.986

1.006

0.4450

0.996

0.978

1.015

0.6955

Global health status

0.984

0.970

0.998

0.0250

0.960

0.932

0.990

0.0088

Fatigue

1.006

0.995

1.016

0.2874

1.002

0.973

1.031

0.9111

Nausea / Vomiting

1.012

0.996

1.028

0.1382

1.017

0.985

1.049

0.3077

Pain

1.007

0.999

1.016

0.0955

1.018

0.992

1.045

0.1828

Dyspnoea

1.007

0.994

1.020

0.2738

1.018

0.997

1.038

0.0882

Insomnia

1.003

0.992

1.014

0.6502

0.994

0.979

1.010

0.4795

Appetite loss

1.007

0.996

1.017

0.2027

0.996

0.967

1.026

0.7874

Constipation

1.002

0.990

1.013

0.7756

0.986

0.966

1.005

0.1494

Diarrhoea

0.994

0.974

1.014

0.5714

0.997

0.971

1.024

0.8285

Financial Problems

0.990

0.971

1.009

0.2845

0.977

0.950

1.004

0.0922

BR Body image

0.992

0.978

1.006

0.2724

0.997

0.978

1.016

0.7507

BR Sexual functioning

0.993

0.976

1.009

0.3856

0.995

0.976

1.014

0.5827

BR Future perspective

0.987

0.975

1.000

0.0510

0.990

0.974

1.007

0.2678

BR Systemic therapy

1.013

0.998

1.029

0.0888

1.008

0.977

1.040

0.6281

BR Breast symptoms

1.005

0.989

1.022

0.5249

1.007

0.986

1.027

0.5268

BR Arm symptoms

1.008

0.990

1.027

0.3686

0.996

0.973

1.020

0.7320

BR Hair loss

0.988

0.977

0.999

0.0355

0.982

0.931

1.036

0.5133

BR Sexual enjoyment

0.993

0.984

1.001

0.0988

0.997

0.978

1.016

0.7507

  1. Legends: OS Overall Survival, HR Hazard ratio