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Fig. 2 | BMC Cancer

Fig. 2

From: CD73 blockade enhances the local and abscopal effects of radiotherapy in a murine rectal cancer model

Fig. 2

Anti-tumor effects of radiation therapy (RT) or anti-CD73 antibody used alone. Tumor bearing mice received local RT to subcutaneous (sc) tumors (3 fractions of 4 Gy) as described above on days 12, 14, 16 and intraperitoneal injection of 200 μg anti-CD73 mAb or Rat IgG2a isotype control at days 12, 14, 16, 19, 22 and 25. All of the mice were sacrificed on day 28, and the weight of sc tumors and number of macroscopic metastatic nodules in the lungs evaluated. P value was calculated with one-way ANOVA followed by Tukey test and * showed p < 0.05

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