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Table 5 Univariate analysis of factors influencing local control

From: Radiosurgery and fractionated stereotactic body radiotherapy for patients with lung oligometastases

Covariate

HR (95% CI)

p-value

Time between diagnosis of LM and SBRT (months)

 <12

1

 

 ≥12

2.5 (1.1-6.0)

0.027

Location of LM

 central

1

 

 peripheral

0.7 (0.2-1.7)

0.412

Histology

 CRC

1

 

 non-CRC

0.2 (0.1-0.6)

0.004

LM diameter (mm)

 ≤10

1

 

 >10

2.2 (0.8-6.6)

0.150

PTV (cm3)

 ≤10

1

 

 >10

3.3 (0.9-11.3)

0.053

Fractionation regimens

 SFRS

1

 

 fSBRT

2.7 (1.0-7.0)

0.037

BED

 <100Gy

1

 

 ≥100 Gy

2.7 (1.1-6.4)

0.021

  1. HR Hazard ratio, CI confidence interval, LM. lung metastases, SBRT stereotactic body radiotherapy, SFRS single fraction radiosurgery, fSBRT fractionated stereotactic body radiotherapy, PTV Planning target volume, BED biologically effective dose