Fig. 5
From: Independence of HIF1a and androgen signaling pathways in prostate cancer
The global genomic distribution of the histone markers, H3K4me1 and H3K4me3, in the LNCaP ChIP-seq analysis. The distribution of the H3K4me1 marker did not change with androgen treatment or hypoxia (a-d). Hypoxia decreased H3K4me3 markers within promoter regions (e vs g). Synthetic androgen R1881 increased the location of H3K4me3 markers within promoter regions under normoxia (e vs f) and hypoxia (g vs h)