Fig. 4

Conservation of AR and HIF binding sites. a, The majority of AR binding sites were conserved following androgen treatment. Of the 35,320 AR called peaks in the normoxic ethanol vehicle control 86% were conserved in the normoxic R1881 treated cells (left). Of the 18,404 AR called peaks in the hypoxic ethanol vehicle control 79% were conserved in the hypoxic androgen treated cells under (right). b, HIF binding sites were not conserved upon hypoxic exposure. Of the 523 HIF called peaks in the normoxic androgen cells 3% were conserved in the hypoxic androgen treated cells under (left). Of the 1181 HIF called peaks in the normoxic ethanol vehicle control 6% were conserved in the hypoxic ethanol vehicle control cells (right)