Fig. 3
From: Independence of HIF1a and androgen signaling pathways in prostate cancer
Genes upregulated by androgen (R1881), hypoxia and HIF1a in LNCaP cells. a, 47 genes upregulated by androgen (LNCaP vehicle control vs. LNCaP R1881, right circle) were independently upregulated by hypoxia (LNCaP normoxia vs. LNCaP 1% hypoxia, left circle). b, 7 genes upregulated by HIF1a overexpression (LNCaP Empty vs. LNCaP HIF1a, left circle) were also independently upregulated by androgen (LNCaP Empty vehicle control vs. LNCaP Empty R1881, right circle). Three genes were independently upregulated by and androgen, hypoxia and HIF1a (SPRED1, NDRG1 and IGFBP)