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Fig. 2 | BMC Cancer

Fig. 2

From: Independence of HIF1a and androgen signaling pathways in prostate cancer

Fig. 2

HIF1a accelerated tumor growth in non-castrated (full) and castrated mice. A, tumor xenografts derived from the LNCaP/HIF1a clone 1 cell line showed accelerated growth in full and castrated mice however LNCaP/HIF1a tumors grew significantly slower in the castrated mouse compared to the full mouse model. In the castrated mice LNCaP/HIF1a tumors continued to grow whilst the empty control clone regressed (data points represent the mean ± SEM, two-way ANOVA; **p < 0.01)

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