Fig. 2From: Independence of HIF1a and androgen signaling pathways in prostate cancerHIF1a accelerated tumor growth in non-castrated (full) and castrated mice. A, tumor xenografts derived from the LNCaP/HIF1a clone 1 cell line showed accelerated growth in full and castrated mice however LNCaP/HIF1a tumors grew significantly slower in the castrated mouse compared to the full mouse model. In the castrated mice LNCaP/HIF1a tumors continued to grow whilst the empty control clone regressed (data points represent the mean ± SEM, two-way ANOVA; **p < 0.01)Back to article page