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Table 4 Hematopoietic reconstitution - multivariate analysis

From: Low-dose peripheral blood stem cell graft after high-dose chemotherapy - an evaluation of hematopoietic reconstitution

ParameterLeukocyte reconstitution (≥1.0 × 109/L)AplasiaPlatelet reconstitution (≥20 × 109/L)Platelet reconstitution (≥50 × 109/L)
n analyzed13010313176
 HR (CI95)P valueHR (CI95)P valueHR (CI95)P valueHR (CI95)P value
Age at ABSCT (≤60 vs. > 60 years)1.038 (0.730–1.476)0.8371.101 (0.725–1.669)0.6521.086 (0.762–1.547)0.6490.841 (0.529–1.336)0.463
Remission pre ABSCT (CR/nCR/VGPR vs. PR/MR/SD/PD)0.989 (0.681–1.436)0.9521.129 (0.735–1.734)0.5811.098 (0.755–1.598)0.6251.060 (0.650–1.729)0.815
G-CSF support (no vs. yes)16.742 (8.514–32.923)< 0.0019.634 (5.425–17.107)< 0.0011.365 (0.951–1.958)0.0911.084 (0.655–1.794)0.753
CD34+ cells/kg bw transplanted (3–4 vs. 2–2.5 × 106)0.607 (0.416–0.885)0.0100.573 (0.375–0.875)0.0100.438 (0.299–0.642)< 0.0010.442 (0.258–0.755)0.003
  1. ASCT autologous blood stem cell transplantation; CI confidence interval; CR complete remission; HR hazard ratio; G-CSF granulocyte-colony stimulating factor; MR minimal response; nCR near complete remission; PD progressive disease; PR partial remission; SD stable disease; VGPR very good partial remission; vs., versus