Table 3 Adverse effects in patients with LCH treated with MA regimen
Adverse Effects | No. (%) |
|---|---|
Hematological toxicity | |
 Neutropenia | 29 (80.6%) |
  Grade 2 | 1 (2.8%) |
  Grade 3 | 5 (13.9%) |
  Grade 4 | 23 (63.9%) |
 Thrombocytopenia | 15 (41.7%) |
  Grade 1 | 1 (2.8%) |
  Grade 2 | 2 (5.6%) |
  Grade 3 | 5 (13.9%) |
  Grade 4 | 7 (19.4%) |
Non-hematological toxicity | |
 Allergic reaction | 8 (22.2%) |
  Grade 1 | 1 (2.8%) |
  Grade 2 | 7 (19.4%) |
 Liver function abnormality | 3 (8.3%) |
  Grade 2 | 3 (8.3%) |
 Nausea | 5 (13.9%) |
  Grade 1 | 1 (2.8%) |
  Grade 2 | 4 (11.1%) |
 Vomit | 3 (8.3%) |
  Grade 1 | 2 (5.6%) |
  Grade 2 | 1 (2.8%) |
 Diarrhea | 3 (8.3%) |
  Grade 1 | 3 (8.3%) |
 Infection event | 4 (11.1%) |
  Grade 2 | 2 (1 case of gingival, and 1 case of skin) |
  Grade 3 | 2 (1 case of lung, and 1 case of digestive tract) |