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Table 2 Response to therapy and organ assessment

From: The combination of methotrexate and cytosine arabinoside in newly diagnosed adult Langerhans cell histiocytosis: a prospective phase II interventional clinical trial

Cycles of chemotherapy

6

Patients available for survival analysis

36

Follow-up (mon)

44 (31–59)

EFS (mon)

39.5 (12–59)

Recurrence

10

Death

1 (death from disease progression)

Response (available for response evaluation)

36

 Better

36

 Complete resolution (NAD)

6

 Regressive disease

30

Organ resolution

 Bone lesions (imaging evaluation)

31

 CR

12

 PR

19

 Bone aching

18

  Complete regression

14

  Partial regression

4

 CNS lesions (imaging evaluation)

25

 CR

13

 PR

12