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Table 2 Correlations between surrogate endpoints and OS in localized Ewing sarcoma

From: A meta-analytic evaluation of the correlation between event-free survival and overall survival in randomized controlled trials of newly diagnosed Ewing sarcoma

Surrogate endpointR2 (95% CI)ρ (95% CI)P-value
EFS0.818 (0.625–1.00)0.929 (0.584–0.990)0.0025
1-year EFS0.436 (0.00–0.873)0.750 (−0.007–0.961)0.052
3-year EFS0.807 (0.604–1.00)0.857 (0.294–0.979)0.014
5-year EFS0.772 (0.537–1.00)0.929 (0.584–0.990)0.0025
1-year OS0.136 (0.00–0.535)0.257 (−0.701–0.884)0.62
3-year OS0.858 (0.693–1.00)0.943 (0.559–0.994)0.0048
5-year OS0.895 (0.778–1.00)0.929 (0.584–0.990)0.0025
  1. Abbreviations: CI confidence interval; OS overall survival; EFS event-free survival