A meta-analytic evaluation of the correlation between event-free survival and overall survival in randomized controlled trials of newly diagnosed Ewing sarcoma

Table 2 Correlations between surrogate endpoints and OS in localized Ewing sarcoma

Surrogate endpoint	R² (95% CI)	ρ (95% CI)	P-value
EFS	0.818 (0.625–1.00)	0.929 (0.584–0.990)	0.0025
1-year EFS	0.436 (0.00–0.873)	0.750 (−0.007–0.961)	0.052
3-year EFS	0.807 (0.604–1.00)	0.857 (0.294–0.979)	0.014
5-year EFS	0.772 (0.537–1.00)	0.929 (0.584–0.990)	0.0025
1-year OS	0.136 (0.00–0.535)	0.257 (−0.701–0.884)	0.62
3-year OS	0.858 (0.693–1.00)	0.943 (0.559–0.994)	0.0048
5-year OS	0.895 (0.778–1.00)	0.929 (0.584–0.990)	0.0025

Abbreviations: CI confidence interval; OS overall survival; EFS event-free survival

ISSN: 1471-2407