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Table 2 Correlation between the preoperative FPR and FAR with clinicopathological features in gastric cancer patients

From: The prognostic value of preoperative fibrinogen-to-prealbumin ratio and a novel FFC score in patients with resectable gastric cancer

VariablesFPRP valueFARP valueCEAP value
 <  0.0145,
n (%)
≥ 0.0145,
n (%)
<  0.0784,
n (%)
≥ 0.0784,
n (%)
≤ 5 ng/ml,
n (%)
>  5 ng/ml,
n (%)
Gender  0.271  1.000  1.000
Male122 (74.8)75 (68.2) 106 (72.1)91 (72.2) 159 (71.9)38 (73.1) 
Female41 (25.2)35 (31.8) 41 (27.9)35 (27.8) 62 (28.1)14 (26.9) 
Age (years)  0.013  0.002  0.277
<  60101 (62.0)51 (46.4) 95 (64.6)57 (45.2) 127 (57.5)25 (48.1) 
≥ 6062 (38.0)59 (53.6) 52 (35.4)69 (54.8) 94 (42.5)27 (51.9) 
Pathological differentiation  0.594  0.692  0.313
Moderate+Well51 (31.3)31 (28.2) 46 (31.3)36 (28.6) 63 (28.5)19 (36.5) 
Poor112 (68.7)79 (71.8) 101 (68.7)90 (71.4) 158 (71.5)33 (63.5) 
Tumor size (cm)  0.001  < 0.001  0.160
<  5110 (67.5)51 (46.4) 103 (70.1)58 (46.0) 135 (61.1)26 (50.0) 
≥ 553 (32.5)59 (53.6) 44 (29.9)68 (54.0) 86 (38.9)26 (50.0) 
Invasion depth  0.006  < 0.001  < 0.001
T1 + T264 (39.3)25 (22.8) 63 (42.9)26 (20.6) 82 (37.1)7 (13.5) 
T3 + T499 (60.7)85 (77.2) 84 (57.1)100 (79.4) 139 (62.9)45 (86.5) 
Lymph nodes metastasis  < 0.001  < 0.001  0.350
Negative81 (49.7)30 (27.3) 75 (51.0)36 (28.6) 93 (42.1)18 (34.6) 
Positive82 (50.3)80 (72.7) 72 (49.0)90 (71.4) 128 (57.9)34 (65.4) 
TNM stage  < 0.001  <  0.001  0.003
I50 (30.7)16 (14.5) 49 (33.3)17 (13.5) 62 (28.1)4 (7.7) 
II53 (32.5)25 (22.7) 46 (31.3)32 (25.4) 56 (25.3)22 (42.3) 
III60 (36.8)69 (62.8) 52 (35.4)77 (61.1) 103 (46.6)26 (50.0) 
CA199 (U/ml)  0.746  1.000  0.002
≤ 37136 (83.4)90 (81.8) 122 (83.0)104 (82.5) 191 (86.4)35 (67.3) 
>  3727 (16.6)20 (18.2) 25 (17.0)22 (17.5) 30 (13.6)17 (32.7) 
Borrmann type  0.009  < 0.001  0.149
038 (23.3)8 (7.3) 38 (25.9)8 (6.3) 43 (19.5)3 (5.8) 
I21 (12.9)18 (16.4) 17 (11.6)22 (17.5) 30 (13.6)9 (17.3) 
II19 (11.7)18 (16.4) 12 (8.1)25 (19.8) 30 (13.6)7 (13.4) 
III71 (43.5)59 (53.6) 68 (46.3)62 (49.2) 100 (45.2)30 (57.7) 
IV14 (8.6)7 (6.3) 12 (8.1)9 (7.2) 18 (8.1)3 (5.8) 
Body mass index (kg/m2)  0.085  0.013  0.508
<  24105 (64.4)82 (74.5) 91 (61.9)96 (76.2) 149 (67.4)38 (73.1) 
≥ 2458 (35.6)28 (25.5) 56 (38.1)30 (23.8) 72 (32.6)14 (26.9) 
Anemia status  0.001  < 0.001  0.493
Negative130 (79.8)66 (60.0) 119 (81.0)77 (61.1) 161 (72.9)35 (67.3) 
Positive33 (20.2)44 (40.0) 28 (19.0)49 (38.9) 60 (27.1)17 (32.7) 
  1. CEA carcinoembryonic antigen; CA199 carbohydrate antigen 199; FPR fibrinogen-to-prealbumin ratio; FAR fibrinogen-to-albumin ratio