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Table 5 GO enrichment analysis results for miR-106b

From: Biomarker roles identification of miR-106 family for predicting the risk and poor survival of colorectal cancer

BP

 GO terms

Genes

P-value

  Transcription, DNA-templated

309

4.29E-12

  Protein ubiquitination

82

1.53E-10

  Negative regulation of transcription from RNA polymerase II promoter

135

3.84E-10

  Viral process

66

4.52E-08

  Protein polyubiquitination

47

5.79E-08

  Protein ubiquitination involved in ubiquitin-dependent protein catabolic process

41

1.15E-07

  Cellular response to DNA damage stimulus

49

4.09E-07

  Cell-cell adhesion

59

4.12E-07

  Positive regulation of transcription, DNA-templated

94

7.99E-07

  Positive regulation of transcription from RNA polymerase II promoter

157

8.43E-07

CC

GO terms

Genes

P-value

  Nucleoplasm

509

4.53E-41

  Nucleus

817

4.14E-36

  Cytoplasm

762

8.37E-28

  Cytosol

512

2.68E-22

  Membrane

337

2.06E-13

  Nucleolus

153

6.39E-11

  Cell-cell adherens junction

70

8.52E-09

  Intracellular membrane-bounded organelle

100

1.50E-07

  Midbody

35

3.50E-07

 Perinuclear region of cytoplasm

103

3.83E-06

MF

GO terms

Genes

P-value

  Protein binding

1251

6.93E-44

  Poly(A) RNA binding

211

5.55E-15

  Ubiquitin-protein transferase activity

81

5.55E-12

  Ubiquitin protein ligase binding

70

2.73E-10

  Ubiquitin protein ligase activity

52

5.74E-10

  Cadherin binding involved in cell-cell adhesion

67

7.22E-09

  Transcription factor activity, sequence-specific DNA binding

155

1.02E-06

  DNA binding

246

1.35E-06

  ATP binding

221

3.40E-06

  Protein serine/threonine kinase activity

72

4.18E-06

  1. GO gene ontology, BP biological process, CC cellular component, MF molecular function