Table 4 Age-dependent incidence rate ratios of different cancer types comparing the entire FCCTX cohort with the Lynch syndrome cohort

Urothelial cancer

0–29

###

0.00

11.07

0.2817

30–49

###

0.00

0.65

0.0009*

50–69

###

0.05

0.24

< 0.0001*

70+

###

0.14

0.72

0.0003*

Non-melanoma skin tumours

0–29

NA

0.00

Inf

1.0000

30–49

###

0.01

0.73

0.0012*

50–69

###

0.06

0.46

< 0.0001*

70+

###

0.06

0.94

0.0046*

Brain tumours

0–29

###

0.05

20.46

1.0000

30–49

###

0.05

1.04

0.0102*

50–69

###

0.09

1.31

0.0283

70+

NA

0.16

Inf

0.5993

Gastric cancer

0–29

NA

0.00

Inf

1.0000

30–49

###

0.12

5.51

0.7383

50–69

###

0.02

0.55

0.0001*

70+

###

0.10

2.38

0.1672

Ovarian cancer

0–29

NA

0.05

Inf

0.5384

30–49

###

0.00

0.22

< 0.0001*

50–69

###

0.16

3.98

0.5594

70+

NA

0.09

Inf

1.0000

Endometrial cancer

0–29

NA

0.00

Inf

1.0000

30–49

###

0.00

0.04

< 0.0001*

50–69

###

0.01

0.08

< 0.0001*

70+

###

0.03

1.92

0.0441

Kidney cancer

0–29

NA

0.00

Inf

1.0000

30–49

###

0.00

156.30

0.5500

50–69

###

0.05

0.91

0.0038*

70+

###

0.02

8.29

0.2207

Small bowel cancer

0–29

NA

0.00

Inf

1.0000

30–49

###

0.00

0.66

0.0009*

50–69

###

0.00

0.43

0.0001*

70+

###

0.00

4.47

0.0843