Skip to main content

Table 4 Age-dependent incidence rate ratios of different cancer types comparing the entire FCCTX cohort with the Lynch syndrome cohort

From: Broadening risk profile in familial colorectal cancer type X; increased risk for five cancer types in the national Danish cohort

  FCCTX vs. Lynch syndrome
CancerAge groupsIRR95% CI lower95% CI UpperP values
Urothelial cancer0–29###0.0011.070.2817
30–49###0.000.650.0009*
50–69###0.050.24< 0.0001*
70+###0.140.720.0003*
Non-melanoma skin tumours0–29NA0.00Inf1.0000
30–49###0.010.730.0012*
50–69###0.060.46< 0.0001*
70+###0.060.940.0046*
Brain tumours0–29###0.0520.461.0000
30–49###0.051.040.0102*
50–69###0.091.310.0283
70+NA0.16Inf0.5993
Gastric cancer0–29NA0.00Inf1.0000
30–49###0.125.510.7383
50–69###0.020.550.0001*
70+###0.102.380.1672
Ovarian cancer0–29NA0.05Inf0.5384
30–49###0.000.22< 0.0001*
50–69###0.163.980.5594
70+NA0.09Inf1.0000
Endometrial cancer0–29NA0.00Inf1.0000
30–49###0.000.04< 0.0001*
50–69###0.010.08< 0.0001*
70+###0.031.920.0441
Kidney cancer0–29NA0.00Inf1.0000
30–49###0.00156.300.5500
50–69###0.050.910.0038*
70+###0.028.290.2207
Small bowel cancer0–29NA0.00Inf1.0000
30–49###0.000.660.0009*
50–69###0.000.430.0001*
70+###0.004.470.0843
  1. *Significant p values following Bonferoni correction