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Table 1 Age-dependent incidence rate ratios of different cancer types comparing the entire FCCTX cohort to the age and sex-matched population-based cohorts

From: Broadening risk profile in familial colorectal cancer type X; increased risk for five cancer types in the national Danish cohort

  

FCCTX vs. Population-based cohort

Cancer

Age groups

IRR

95% CI lower

95% CI Upper

P values

Breast cancer (n = 103)

0–29

0.00

0.00

21.39

1.0000

30–49

1.71

1.02

2.68

0.0070*

50–69

1.54

1.06

2.14

0.0030*

70+

1.37

0.72

2.34

0.1495

Urothelial cancer (n = 45)

0–29

10.01

0.06

73.02

0.0955

30–49

0.50

0.00

3.62

1.0000

50–69

0.90

0.41

1.70

0.7999

70+

2.10

1.26

3.30

0.0003*

Lung cancer (n = 40)

0–29

0.00

0.00

81.72

1.0000

30–49

1.20

0.27

3.32

0.6186

50–69

0.50

0.26

0.87

0.0011*

70+

0.65

0.31

1.17

0.0864

Pancreatic cancer (n = 21)

0–29

0.00

0.00

348.69

1.0000

30–49

0.00

0.00

5.75

1.0000

50–69

1.05

0.32

2.51

0.8450

70+

2.21

1.12

4.38

0.0023*

Gastric cancer (n = 20)

0–29

0.00

0.00

136.20

1.0000

30–49

5.87

1.57

15.02

0.0007*

50–69

0.77

0.14

2.35

0.8254

70+

1.81

0.70

3.80

0.0811

Eye tumours (n = 5)

0–29

0.00

0.00

40.95

1.0000

30–49

0.00

0.00

18.09

1.0000

50–69

7.73

1.76

21.45

0.0006*

70+

0.00

0.00

15.20

1.0000

  1. *Significant p values following Bonferoni correction