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Table 1 Age-dependent incidence rate ratios of different cancer types comparing the entire FCCTX cohort to the age and sex-matched population-based cohorts

From: Broadening risk profile in familial colorectal cancer type X; increased risk for five cancer types in the national Danish cohort

  FCCTX vs. Population-based cohort
CancerAge groupsIRR95% CI lower95% CI UpperP values
Breast cancer (n = 103)0–290.000.0021.391.0000
30–491.711.022.680.0070*
50–691.541.062.140.0030*
70+1.370.722.340.1495
Urothelial cancer (n = 45)0–2910.010.0673.020.0955
30–490.500.003.621.0000
50–690.900.411.700.7999
70+2.101.263.300.0003*
Lung cancer (n = 40)0–290.000.0081.721.0000
30–491.200.273.320.6186
50–690.500.260.870.0011*
70+0.650.311.170.0864
Pancreatic cancer (n = 21)0–290.000.00348.691.0000
30–490.000.005.751.0000
50–691.050.322.510.8450
70+2.211.124.380.0023*
Gastric cancer (n = 20)0–290.000.00136.201.0000
30–495.871.5715.020.0007*
50–690.770.142.350.8254
70+1.810.703.800.0811
Eye tumours (n = 5)0–290.000.0040.951.0000
30–490.000.0018.091.0000
50–697.731.7621.450.0006*
70+0.000.0015.201.0000
  1. *Significant p values following Bonferoni correction