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Table 4 Abnormal biochemical results and symptoms among study subjects

From: Prevalence and significance of potential drug-drug interactions among cancer patients receiving chemotherapy

Laboratory test

Patients: n (%)

Hematological tests

 Hemoglobin

   < 12 g/dL

398 (58.7)

 Red blood cells

   < 4 × 106/mm3

118 (17.4)

   > 5.5 × 106/mm3

11 (1.6)

 Total leukocyte count

   < 4000 /mm3

96 (14.2)

   > 11,000 /mm3

145 (21.4)

 Platelet count

   < 150,000 /mm3

138 (20.4)

   > 450,000 /mm3

63 (9.3)

 Neutrophils

   < 40%

70 (10.3)

   > 75%

113 (16.7)

 Lymphocytes

   < 20%

149 (21.9)

   > 45%

91 (13.4)

 Eosinophils

   < 1%

47 (6.9)

   > 6%

17 (2.5)

 Monocytes

   < 6%

372 (54.9)

   > 10%

23 (3.4)

Renal function tests

 Serum creatinine

   > 1.3 mg/dl

26 (3.8)

  Total bilirubin

> 1.5 mg/dl

12 (1.8)

Liver function tests

 Alanine aminotransferase

   > 40 U/L

121 (17.8)

 Aspartate aminotransferase

   > 40 U/L

46 (6.8)

 Alkaline phosphatase

   < 35 U/L

3 (0.4)

   > 130 U/L

106 (15.6)

Symptoms

 Fever

82 (12.1)

 Generalized body aches

63 (9.3)

 Nausea and vomiting

32 (4.7)

 Abdominal pain

28 (4.1)

 Cough

26 (3.8)

 Anorexia

19 (2.8)

 Shortness of breath

15 (2.2)

 Generalized weakness

11 (1.6)

 Pallor

11(1.6)

 Swelling in different body parts

10 (1.5)

 Bleeding from different body parts

9 (1.3)

 Loose motions

10 (1.3)

 Abdominal distension

8 (1.2)

 Epigastric pain

9 (1.2)

 Dysphagia

10 (1.2)

 Sweating

11 (1.2)

 Urinary tract infections

12 (1.2)