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Table 5 PD-L1 expression stratified by clinicopathologic features

From: Cytology cell blocks from malignant pleural effusion are good candidates for PD-L1 detection in advanced NSCLC compared with matched histology samples

Characteristic PD-L1 TPS Total (n) Z P value
< 1% n (%) 1–49% n (%) ≥50% n (%)
Total 32 (25.8) 45 (36.3) 47 (37.9) 124   
Age, y     124 −1.038 0.299
  ≤ 55 13 (29.5) 17 (38.6) 14 (31.8)    
  > 55 19 (23.8) 28 (35) 33 (41.3)    
Sex     124 −1.099 0.272
 Male 23 (28.8) 29 (36.3) 28 (35.0)    
 Female 9 (20.5) 16 (36.4) 19 (43.2)    
Diagnosis     119 −2.47 0.013a
 Adenocarcinoma 23 (21.3) 42 (38.9) 43 (39.8) 108   
  Smoking status     99 −1.944 0.052
   Current or former 13 (32.5) 15 (37.5) 12 (30.0)    
   Never 9 (15.3) 24 (40.7) 26 (44.1)    
 Squamous cell carcinoma 7 (63.6) 2 (18.2) 2 (18.2) 11   
  Smoking status     8 −0.77 0.643
   Current or former 4 (66.7) 2 (33.3) 0 (0.0)    
   Never 1 (50.0) 0 (0.0) 1 (50.0)    
Smoking status     111 −2.63 0.009a
 Current or former 19 (38.0) 18 (36.0) 13 (26.0)    
 Never 10 (16.4) 24 (39.3) 27 (44.3)    
  1. Abbreviation: PD-L1 programmed cell death ligand-1, TPS tumor proportion score; astatistically significant