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Table 5 PD-L1 expression stratified by clinicopathologic features

From: Cytology cell blocks from malignant pleural effusion are good candidates for PD-L1 detection in advanced NSCLC compared with matched histology samples

CharacteristicPD-L1 TPSTotal (n)ZP value
< 1% n (%)1–49% n (%)≥50% n (%)
Total32 (25.8)45 (36.3)47 (37.9)124  
Age, y   124−1.0380.299
  ≤ 5513 (29.5)17 (38.6)14 (31.8)   
  > 5519 (23.8)28 (35)33 (41.3)   
Sex   124−1.0990.272
 Male23 (28.8)29 (36.3)28 (35.0)   
 Female9 (20.5)16 (36.4)19 (43.2)   
Diagnosis   119−2.470.013a
 Adenocarcinoma23 (21.3)42 (38.9)43 (39.8)108  
  Smoking status   99−1.9440.052
   Current or former13 (32.5)15 (37.5)12 (30.0)   
   Never9 (15.3)24 (40.7)26 (44.1)   
 Squamous cell carcinoma7 (63.6)2 (18.2)2 (18.2)11  
  Smoking status   8−0.770.643
   Current or former4 (66.7)2 (33.3)0 (0.0)   
   Never1 (50.0)0 (0.0)1 (50.0)   
Smoking status   111−2.630.009a
 Current or former19 (38.0)18 (36.0)13 (26.0)   
 Never10 (16.4)24 (39.3)27 (44.3)   
  1. Abbreviation: PD-L1 programmed cell death ligand-1, TPS tumor proportion score; astatistically significant