Cytology cell blocks from malignant pleural effusion are good candidates for PD-L1 detection in advanced NSCLC compared with matched histology samples

Table 2 PD-L1 expression in MPE cell blocks and matched histology samples

Type	Tumor proportion score of PD-L1			Total (n)	Coincidence rate (%)	P value
Type	< 1%, n (%)	1–49%, n (%)	≥50%, n (%)	Total (n)	Coincidence rate (%)	P value
MPE cell block	23 (22.8)	38 (37.6)	40 (39.6)	101	85.1	0.005^a
Histology sample	26 (25.7)	44 (43.6)	31 (30.7)	101	85.1	0.005^a
Surgical resection	3 (27.3)	5 (45.5)	3 (27.3)	11	72.7	0.564
Biopsy	20 (24.1)	38 (45.8)	25 (30.1)	83	85.5	0.005^a
EBUS-TBNA	3 (42.9)	1 (14.3)	3 (42.9)	7	100	1.000

Abbreviations: PD-L1 programmed cell death ligand-1, MPE malignant pleural effusion; EBUS-TBNA, endobronchial ultrasound-guided transbronchial needle aspiration biopsy; ^astatistically significant

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