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Table 7 The distribution of the haplotypes constructed by SNPs in ERAP2 gene

From: Polymorphisms in endoplasmic reticulum aminopeptidase genes are associated with cervical cancer risk in a Chinese Han population

Haplotypes

Control (Freq)

CIN (Freq)

Cervical cancer (Freq)

Cervical cancer vs Control

CIN vs Control

Cervical cancer vs CIN

P-value

OR[95%CI]

P-value

OR[95%CI]

P-value

OR[95%CI]

G-A-A-G-C

953.78 (37.8%)

411.75 (37.0%)

784.87 (36.6%)

0.219

1.080 [0.955–1.220]

0.908

0.991 [0.852–1.153]

0.336

1.079 [0.925–1.258]

G-A-A-G-T

58.71 (2.3%)

20.26 (1.8%)

72.44 (3.4%)

0.009

1.592 [1.122–2.258]

0.053

1.837 [0.983–3.434]

0.006

2.000 [1.215–3.292]

G-T-A-G-C

61.18 (2.4%)

25.61 (2.3%)

71.82 (3.3%)

0.018

1.513 [1.070–2.139]

0.638

1.130 [0.678–1.884]

0.055

1.560 [0.987–2.465]

T-T-G-A-T

1346.11 (53.3%)

586.29 (52.7%)

973.03 (45.4%)

0.003

0.835 [0.740–0.942]

0.908

1.009 [0.868–1.173]

0.009

0.817 [0.702–0.951]

  1. Note: The statistical significant threshold was set at P < 0.012 (0.05/n, n = 4) after Bonferroni correction