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Table 5 Results of the multivariable regression analyses for the EORTC QLQ-C30 (p < 0.05)

From: The association of depressive symptoms, personality traits, and sociodemographic factors with health-related quality of life and quality of life in patients with advanced-stage lung cancer: an observational multi-center cohort study

Independent variablesNBSEβP-valueCorrected P-valuea95% CI for BR2
 General Health Status/Quality of Life
 Employment: yes versus no job11610.4054.3580.1830.0190.0761.764,
19.045
0.417
 CES-D −2.0620.314−0.627< 0.001< 0.001−2.684,
−1.439
 
 Physical functioning
 Employment: no versus having a job11710.6843.8850.2040.0070.0212.981,
18.386
0.453
 ECOG: 0 to 1 versus 2 or higher −23.5865.958−0.304< 0.001< 0.001−35.398,
−11.775
 
CES-D −1.3570.284−0.449< 0.001< 0.001−1.921,
− 0.793
 
 Role functioning
 ECOG: 0 to 1 versus 2 or higher120−30.8907.975−0.299< 0.001< 0.001−46.692,
−15.088
0.414
 CES-D −2.1970.384−0.542< 0.001< 0.001− 2.957,
−1.437
 
 STAI Trait 1.8400.6870.2950.0090.0240.479,
3.201
 
 Emotional functioning
 CES-D117−2.0440.222−0.668< 0.001< 0.001−2.483,
−1.604
0.655
 Cognitive functioning
 Educational level: low versus high1299.3444.0600.1700.0230.0691.307,
17.382
0.359
 CES-D −1.5720.274−0.536< 0.001< 0.001−2.114,
− 1.030
 
 Social functioning
 Partner status: no partner versus having a partner116−12.7865.817−0.1740.0300.090−24.318,
−1.253
0.370
 ECOG: 0 to 1 versus 2 or higher −16.7487.367−0.1880.0250.090−31.354,
−2.141
 
 CES-D −1.3940.348−0.401< 0.001< 0.001−2.085,
− 0.704
 
  1. aBenjamini-Hochberg method was used to correct P-values
  2. Abbreviations: EORTC QLQ-C30, European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30, N number of patients, B unstandardized beta, SE standard error, β standardized beta, CI confidence interval, R2 explained varriance, CES-D Center for Epidemiologic Studies Depression Scale, ECOG Eastern Cooperative Oncology Group, STAI State Trait Anxiety Inventory