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Table 5 Results of the multivariable regression analyses for the EORTC QLQ-C30 (p < 0.05)

From: The association of depressive symptoms, personality traits, and sociodemographic factors with health-related quality of life and quality of life in patients with advanced-stage lung cancer: an observational multi-center cohort study

Independent variables

N

B

SE

β

P-value

Corrected P-valuea

95% CI for B

R2

 

General Health Status/Quality of Life

 Employment: yes versus no job

116

10.405

4.358

0.183

0.019

0.076

1.764,

19.045

0.417

 CES-D

 

−2.062

0.314

−0.627

< 0.001

< 0.001

−2.684,

−1.439

 
 

Physical functioning

 Employment: no versus having a job

117

10.684

3.885

0.204

0.007

0.021

2.981,

18.386

0.453

 ECOG: 0 to 1 versus 2 or higher

 

−23.586

5.958

−0.304

< 0.001

< 0.001

−35.398,

−11.775

 

CES-D

 

−1.357

0.284

−0.449

< 0.001

< 0.001

−1.921,

− 0.793

 
 

Role functioning

 ECOG: 0 to 1 versus 2 or higher

120

−30.890

7.975

−0.299

< 0.001

< 0.001

−46.692,

−15.088

0.414

 CES-D

 

−2.197

0.384

−0.542

< 0.001

< 0.001

− 2.957,

−1.437

 

 STAI Trait

 

1.840

0.687

0.295

0.009

0.024

0.479,

3.201

 
 

Emotional functioning

 CES-D

117

−2.044

0.222

−0.668

< 0.001

< 0.001

−2.483,

−1.604

0.655

 

Cognitive functioning

 Educational level: low versus high

129

9.344

4.060

0.170

0.023

0.069

1.307,

17.382

0.359

 CES-D

 

−1.572

0.274

−0.536

< 0.001

< 0.001

−2.114,

− 1.030

 
 

Social functioning

 Partner status: no partner versus having a partner

116

−12.786

5.817

−0.174

0.030

0.090

−24.318,

−1.253

0.370

 ECOG: 0 to 1 versus 2 or higher

 

−16.748

7.367

−0.188

0.025

0.090

−31.354,

−2.141

 

 CES-D

 

−1.394

0.348

−0.401

< 0.001

< 0.001

−2.085,

− 0.704

 
  1. aBenjamini-Hochberg method was used to correct P-values
  2. Abbreviations: EORTC QLQ-C30, European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30, N number of patients, B unstandardized beta, SE standard error, β standardized beta, CI confidence interval, R2 explained varriance, CES-D Center for Epidemiologic Studies Depression Scale, ECOG Eastern Cooperative Oncology Group, STAI State Trait Anxiety Inventory