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Table 3 Results of the univariable regression analyses with the WHOQOL-BREF and EORTC QLQ-C30 domains/scales as dependent variables

From: The association of depressive symptoms, personality traits, and sociodemographic factors with health-related quality of life and quality of life in patients with advanced-stage lung cancer: an observational multi-center cohort study

 WHOQOL-BREFEORTC QLQ-C30
General facetPhysical healthPsychological healthSocial relationshipsEnvironmentGeneral Health Status/QoLPhysical functioningRole functioningEmotional functioningCognitive functioningSocial functioning
Independent variablesβββββββββββ
Age− 0.168**0.0420.0320.0740.069− 0.052− 0.0020.045− 0.0740.0580.120
Gendera−0.011−0.121− 0.0750.185**0.077−0.114− 0.218**− 0.185**− 0.039− 0.163*− 0.105
Marital status: no partner versus having a partnerb−0.078− 0.1010.0390.170**0.079− 0.043− 0.076− 0.038− 0.132− 0.010− 0.163*
Educational level: low versus highc0.0230.0290.0860.1110.170**−0.047−0.006− 0.0080.0460.214**0.024
Ethnicity: Caucasian versus other ethnicityd−0.127−0.023− 0.1030.0490.010−0.056− 0.001−0.018− 0.0340.007− 0.079
Employment: yes versus having no jobe0.218**0.203**0.096−0.0180.0750.257**0.246**0.135*0.1200.148*0.182**
ECOG: 0 to 1 versus 2 or higherf−0.220**− 0.301**−0.197**− 0.211**−0.123− 0.200**−0.311**− 0.319**−0.1270.012−0.220**
CES-D−0.534**−0.575**− 0.653**−0.168**− 0.465**−0.589**− 0.482**−0.525**− 0.786**−0.575**− 0.505**
STAI Trait−0.236− 0.356**−0.518**− 0.225**−0.522**− 0.260**−0.209**− 0.151*−0.597**− 0.341**−0.280**
NEO-FFI neuroticism−0.153*−0.296**− 0.494**−0.230**− 0.389**−0.269**− 0.163*−0.217**− 0.525**−0.276**− 0.231**
NEO-FFI extraversion0.196**0.2100.278**0.216**0.209**0.179**0.179**0.1370.203**0.0160.195**
NEO-FFI openness0.049−0.1320.0020.039−0.059− 0.045−0.114− 0.155*0.058− 0.020−0.067
NEO-FFI agreeableness0.0510.177**0.163*0.1390.198**0.153*0.145*0.1350.240**0.1400.148*
NEO-FFI conscientiousness0.172**0.291**0.314**0.238**0.295**0.242**0.243**0.187**0.181**0.1320.292**
  1. *P-values of p ≤ 0.10
  2. **P-values of p ≤ 0.05
  3. aMale is reference
  4. bNo partner is reference
  5. cLow educational level is reference
  6. dOther ethnicity is reference
  7. eNo job is reference
  8. f0 to 1 is reference
  9. CES-D score, STAI trait score and NEO-FFI scale scores represent continuous variables
  10. Abbreviations: β standardized beta,WHOQOL-BREF, World Health Organization Quality of Life-BREF questionnaire, EORTC QLQ-C30 European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30, ECOG Eastern Cooperative Oncology Group, CES-D Center for Epidemiologic Studies Depression Scale, STAI State Trait Anxiety Inventory, NEO-FFI Neuroticism-Extraversion-Openness Five-Factor Inventory